Liquid Biopsy Diagnostics

AI/ML driven diagnostics from a few drops of blood

Non-invasive, Accurate, and Rapid Detection

Replacing the surgical biopsy with a sample of peripheral venous blood - bringing together a deep understanding of cancer biology and the magic of machine learning algorithms in the diagnosis, monitoring and management of brain tumor patients.

The Science

  • Draw blood for a liquid biopsy.

  • Diagnose brain tumor via DNA, RNA, or protein data from pts blood using CTC, cfDNA or exosomes.

  • Algorithms match known diagnostic tumor profiles with those of blood exosomal across 30,000+ data points.

  • Used to diagnose, prognosticate, monitor, and personalise therapy to treat brain tumors.

Key Advantages

With its minimally invasive procedure and added diagnostic benefits, Liquid Biopsy is a better alternative to surgical biopsy.

  • 1
    Can be performed anywhere

    Unlike traditional biopsies that have be done at a hospital, liquid biopsy can be done at any location - at the comfort of the patient's home, or any other place of their choice.

  • 2
    No surgery required

    Since liquid biopsy is dependant only on blood drawn from the patient, there is no need for surgery. This gives liquid biopsy several advantages over traditional methods.

  • 3
    Reduced risk

    As liquid biopsy is a minimally invasive procedure without subjecting the patient to clinical procedures that traditional methods rely on, there is significantly lesser risk to mortality and paralysis.

  • 4
    Lesser turnaround time

    While traditional methods often take anywhere between 5-7 days for a diagnosis, liquid paralysis is vastly faster, with practitioners often able to make an accurate diagnosis in under 24 hours.

  • 5
    Lower costs

    Traditional methods of diagnosis rely on multiple steps and processes to conclude on the final result, thereby making it significantly more costly than liquid biopsy, which is a much quicker process.

  • 6
    Diagnosis at Different Clinical Stages

    Our tests provide diagnostic insights at multiple stages of disease progression. This allows for timely detection, monitoring, and treatment adjustments based on the clinical needs of the patient.

  • 7
    More than 95% Accuracy

    The process followed for Liquid Biopsy, and the technology that enables the decision making, makes it far superior to traditional methods, increasing the accuracy of diagnosis from 70% to more than 95%.

  • 8
    Heterogeneity Agnostic

    Our test delivers consistent diagnostic results regardless of tumor heterogeneity. It accurately analyzes diverse tumor cell populations to support comprehensive treatment planning.

Process Flow

  • 01
    Order Process

    A doctor orders the Exsegen Gliogen LDx- Adult test when an imaging test results suggest the possibility of a primary brain neoplasm.

  • 02
    Specimen Collection

    Peripheral blood of the patient is collected in blood collection tubes included in the Exsegen Aqua LDx-Adult Kit at a hospital or ambulatory care facility.

  • 03
    Specimen Preparation

    Exosomes are precipitated and RNA is isolated from the collected blood sample.

  • 04
    Sequencing

    Next-Gen Sequencing is used to sequence the RNA. The sequence data is uploaded to a secure server.

  • 05
    AI/ML Analysis

    On the server, the RNA data is compared to an array of such exosomal samples that have been pre-annotated with the tumor type and tumor grade

  • 06
    Report Generation

    An electronic version of the report, specifying the tumor type and tumor grade, is generated on the server with a notification linked to the healthcare facility.

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